I've had all 3. McAfee has gotten ridiculous at times, particularly in pestering you to renew. This new machine with Windows 10 has McAfee. Our internet provider gives us Norton free. When McAfee expires or if it gives me any trouble before, I'm deleting it and putting Norton in place.
Never had any trouble with Kaspersky. It was on my HP notebook when I bought it. When it expired, I went with Norton.
Any of these will give you potential trouble if you only have 4 GB of memory because they hog memory just lurking around. Ever since I went with 8 GB of memory on our computers, I've had no problems.
Even Avast and a couple of other free ones (yes, I tried them) will slow the computer down noticeably with only 4 GB of memory.
Ralph