My wife is doing fine today. picked up 2 new epi pins. they now come 2 with a persciption, they told her since most kids with them have to leave one with the school. I told her about the temperature limit on them.
FOR ALL EPI PEN USERS - I hope you find this helpful. This is supposedly the only long term study done on storage of epi pens.
Long-term stability of epinephrine dispensed in unsealed syringes for the first-aid treatment of anaphylaxis Annals of Allergy, Asthma & Immunology Volume 102, Issue 6, June 2009, Pages 500–503 Background: When epinephrine autoinjectors are unavailable or unaffordable, patients at risk for anaphylaxis in the community are sometimes provided with an unsealed syringe containing a premeasured epinephrine dose for use in first-aid treatment of anaphylaxis episodes.
Objectives: To study the stability of epinephrine solution in unsealed syringes under conditions of high ambient temperature, low vs high humidity, and light vs dark.
Methods: Forty unsealed syringes each containing an epinephrine dose of 0.3 mg (as a 1-mg/mL epinephrine solution) were stored at 38°C for 5 months, with 10 syringes at each of 4 different standardized storage conditions: dark and light at low (15%) humidity and dark and light at high (95%) humidity. Duplicate syringes were removed monthly from each storage environment and analyzed for epinephrine content vs control syringes.
Results: The epinephrine dose, expressed as the percentage remaining of the mean control dose, was below compendial limits (90% to 115% of label claim) by 3 months after storage at 38°C and low humidity and by 4 months after storage at 38°C and high humidity. Light had no significant effect.
Conclusion: In hot climates, if an unsealed syringe prefilled with an epinephrine dose is provided for the first-aid treatment of anaphylaxis, it should be replaced every few months on a regular basis with a new syringe containing a fresh dose of epinephrine.
Storage and Stability Always store EpiPen® or EpiPen® Jr in the carrier tube with the blue safety release on until you need to use it. Store at 25°C (77°F); EXCURSIONS PERMITTED TO 15° - 30°C (59 ° - 86°F). Do not refrigerate. Protect from light. Periodically check to make sure the solution in the auto-injector is not brown in color. Replace if it is discolored or contains a precipitate.