I've got a '97 F350, CC LB 4x4.
When we got it my wife really wanted, and we got, a Bigfoot camper, because we like 4-season camping. I hated driving with that thing on the truck.
She also got a 3' extension tube for the trailer hitch so if we wanted to we could take the horses - as suggested by the camper dealer (who's still in business and sells pusher RVs mostly).
I'm glad to say that A, we never pulled the horse trailer with the camper on the truck and B, only used the camper a small number of times - I much prefer rougher camping and also just how iffy the truck felt with that massive weight on it.
Knowing what I know now, I realize we really dodged a bullet. We were likely right at GVWR on the truck with the camper on it, definitely somewhat over GVWR when fully loaded, and pulling the trailer with it would've really been a bad idea.