Pretty sure that I have read Massad Ayoob stating that you should not use reloads in a duty/carry weapon for legal reasons. The idea is that a lawyer could argue that you created a more powerful round than a commercial round. Well, you can't make a more powerful round unless one violates the round specifications and a decent lawyer could easily prove this fact. On the other hand, you never know what a jury will do and if the case is a border line case, the idea that the round was reloaded by the shooter might be enough to influence the jury in spite of the facts.
I don't believe everything that Ayoob has written and I have seen some decent criticisms of his work so I take what he says with a block of salt. However, I think in this case, his advice is good. I work with lawyers and they try to minimize risk when possible. If Joe shoots someone with a reload, the opposing lawyer can spend time arguing that the reload is more "powerful." Joe's lawyer now has to refute that the round was more "powerful" instead of spending time arguing other parts of the case. The reload could be a distraction and just might be the straw the broke the camel's back.
The odds of anyone on TBN using a weapon for self defense are low, and the odds of being in court over the incident are even lower, however I would never use reloads for defensive purposes since even with today's prices, ammo is pretty cheap compared to the cost of an hour of lawyer time.
Later,
Dan