No 4 speed manual trannies anymore. Last 4 speed manual was many, many years ago. They went to a 5 speed around 30 years ago and then a 6 speed manual about 20 years ago. No manual trannies on any new Ford, Chevy, or Ram pickups period. Last manual tranny for them was in the 2019 Ram. The new Ford Bronco can be optioned with a 7 speed manual tranny but only with the 4 cylinder engine.
As far as I know it is still possible to get a manual shift lever for the transfer case in a basic XL Ford Superduty. Same with the manual locking hubs. The higher trims all have a dial on the dash to shift into 4wd, and I believe those higher trims give you "auto-locking" hubs, but those hubs can also be locked in manually.