I'm not familiar with Iseki's, but I have 3 Yanmars, all of which I have had to start from a dry tank. Two for engine work, and all three from running the tank dry. They were all very easy to re-start after proper use of the bleed screws. In no case did I have to crack open an injection line.
The last time, I was plowing snow with my YM1110D while my 5yr old son was playing in the snow nearby. He called to me, so I idled the tractor back and walked over to him. Before I got back to the tractor, it had run dry and quit. I walked back to the garage, got the 5gal can with the last gallon of diesel I had and a philips head screwdriver. I poured the diesel in, bled the three bleeders in order, turned the key and it fired right up. It was so easy that I don't really worry too much about running out of fuel.