In my years I have had to kill lots of skunks. I tried head shots but they almost all sprayed like crazy. It's something to do with the nerves going crazy. Only one skunk I ever seen killed didn't spray and it was one my cousin shot with a 410 slug and severed its spine right in front of the back legs and went at a angle down thru it chest. I have lately had skunks coming around here and don't want to put up with the smell from shooting them. Been trying different methods. I had one coming from a old building across the road just before sunset and would make noise when I'd saw it coming down the drive and when it would be crossing the road on its way back drop the hammer on some bird shot at his butt, but twice he sprayed each time. Was far enough away it would just pepper his butt a little but that didn't stop him from coming. I tried a water hose and would spray him. They don't like that at all and would run. Trick is don't over do and just enough to make them leave. Just remember the tail comes up means their going to shoot the juice. After a couple times was at least a week or so no skunk. But then here it comes again. So now I have a good squirt bottle and have it so it squirts a stream and use apple cider vinegar. I ran him back across the road and that's been over a month ago and no sign of him since. Further down the road I have a culvert that goes under the road and another one a few days ago came under it before sunset and I got my squirt bottle and ran that one back across the road. A few minutes later the fool crossed the road about fifty yards further down and was in a field I keep cut with a bush hog and the grass was probably 10 inches tall. I ran out there with out my bottle but it just hunkered down and didn't move. So I got my squirt bottle and just a couple squirts and he was across the road. Haven't seen that one again either. You can spray around your garden, in the barn or where ever you don't want the critters and they will stay away. I started using it around the chicken coop and garden and barn and I haven't seen any mice lately. So far I am impressed with it. I would rather smell apple cider vinegar than skunk pee.