I too have the ISOTunes Pro and they're great as far as immediate connecting, blocking noise, sound quality, battery life and comfort.
My only complaint is the actual foam earpieces don't last, maybe a couple of days of 4-5 hours a day. The inner hard plastic that screws onto the stem in the bud bud cracks and won't hold in place. If the replacement cost for the foam earpieces was more realistic I'd get a bunch of them but 'fraid not. As well, they are proprietary and there is no after market available. Screen shot for 5 pair right from ISO Tunes or 3 pair from Lee Valley, ridiculous for some foam.
This is what I use now, they're not noise cancelling but do block a bit so I use them alone when outside messin' around with no/not much noise. If I'm mowing or trimming I use a pair of muffs over them with no discomfort at all as they're inside the foam earpieces.
Well over 8 hours battery life, immediately connect, good sound (not
quite as good as the ISOTunes but more than good enough for a non-audiophile) and if you want to carry the case with you, you can easily carry them in your pocket.
The volume, skip, fast forward etc controls are by tap on either bud so you don't have to root for your phone or in the case of the ISOTunes for the control pod.
The price is more than reasonable and their warranty is awesome. I thought I had a fault with the first pair I had bought ( I didn't, it was my phone) , contacted them and was sent a replacement pair no questions asked.
I did have a pair of these but I've got odd shaped ear holes I guess and after a couple of hours they would start to ache, they worked great but it was me with an odd head that was wrong
.