On our trip this spring from Texas to Washington State and back, we never experienced any problems with bedbugs in any of the Best Western Hotels where we stayed exclusively. We did check for them in each room before bringing in our luggage.
About three years ago for my birthday, my wife gave us a trip to Niagara Falls. We got reservations in an Econo-Lodge Hotel on the American side near the falls, and that was a big, big mistake. The hotel was shabby, overpriced, dirty, and bedbugs were all around the bed and under it. We turned on the lights and must have seen about a dozen of them easily visible around the bed. We got out of there quickly.
What I am hearing is that even some of the big, new, and clean hotels are experiencing problems. The best advice I can give is to keep your bags packed tightly and don't leave clothes hanging in the closets where they can get on them or lay eggs in/on them. I might even suggest that until you know there are no bedbugs, you put your bags in large garbage bags and seal them with tie wraps. This is extreme, but you have to prevent them from being transported place-to-place and especially back to your home. It's easy enough to pack a few garbage bags and dispose of them after leaving the hotel. We check every room we stay in thoroughly to make sure there isn't any infestation.
